ABOUT US

Profile

Beijing CorreGene Biotechnology Co., Ltd

Beijing CorreGene Biotechnology Co., Ltd. is a clinical-stage biotechnology committed to the development of innovative therapies based on T cell receptor (TCR).

CorreGene has established leading platforms for TCR discovery and optimization. TCR discovery platform can support acquisition of TCR for various optimal targets in large scale and low cost. In particular, the SMART-TCR affinity optimization platform, a revolutionary TCR affinity optimization technology, has greatly improved the success rate and efficacy of TCR affinity optimization and broken down the barriers of development TCR innovative drugs.

CorreGene is developing many First-in-class TCR-T cell therapeutic products and soluble TCR-fusion proteins for the treatment of tumors, chronic infections and other indications, including the first cell therapy product targeting KRAS-G12 mutation in China and the world's first TCR-fusion protein therapy for the treatment of HPV infectious diseases. At present, two TCR-T products have launched Investigator Initiated Trials (IIT) program.

In the future, CorreGene will focus on developing and delivery TCR innovative therapies for patients with tumors, chronic infections and autoimmune diseases.

Corporate culture

Mission

Innovating biotechnology to
brighten life with hope

Vision

To be a trustable leading
biopharmaceutical enterprise

Vision

To be a trustable leading
biopharmaceutical enterprise

Core values

Open collaboration, Be determined
to innovate,Realistic and Pragmatic,
pragmatism, Excellent quality

Core team

Core team

Xingwang Xie

Ph.D., MD.

Dr. Xingwang Xie founded CorreGene in 2016 and served as board chairman and CEO since 2019.

Dr. Xie is a member of the Multidisciplinary Tumor Diagnosis (MDD) collaboration group of the Tumor Marker Committee of the Chinese Anti-Cancer Association and a member of the Clinical Application Committee of pharmaceutical biotechnology of the China Medicinal Biotech Association (CMBA).

From 2009 to 2019, Dr. Xie started his career as a scientist at the Peking University People’s Hospital, Peking University Hepatology Institute, and has devoted over 10 years to studying the genomics and immunobiology of cancer and their clinical implications. During this period, Dr. Xie been responsible for several major research programs from the National Natural Science Foundation of China and the Beijing Natural Science Foundation. He was also the core members of several projects from National Science and Technology Major Project.

Dr. Xie have participated in many immunotherapy trails for the treatment of chronic hepatitis and liver cancer, including cell therapies, tumor associated antigen vaccines and tumor neoantigen vaccines. He has published more than 20 papers in peer-reviewed journals and is the inventor of more than 10 patents or computer software copyrights.

Dr. Xie received an MD. (bachelor's degree in clinical medicine) from Medical College of Wuhan University of science and technology in 2006, a master's degree in medicine from the Department of medicine of Peking University in 2009 and a Ph. D. in medicine from China CDC (Center for Disease Control and prevention) in 2018.

Core team

Xingwang Xie2

Ph.D., MD.

Dr. Xingwang Xie founded CorreGene in 2016 and served as board chairman and CEO since 2019.

Dr. Xie is a member of the Multidisciplinary Tumor Diagnosis (MDD) collaboration group of the Tumor Marker Committee of the Chinese Anti-Cancer Association and a member of the Clinical Application Committee of pharmaceutical biotechnology of the China Medicinal Biotech Association (CMBA).

From 2009 to 2019, Dr. Xie started his career as a scientist at the Peking University People’s Hospital, Peking University Hepatology Institute, and has devoted over 10 years to studying the genomics and immunobiology of cancer and their clinical implications. During this period, Dr. Xie been responsible for several major research programs from the National Natural Science Foundation of China and the Beijing Natural Science Foundation. He was also the core members of several projects from National Science and Technology Major Project.

Dr. Xie have participated in many immunotherapy trails for the treatment of chronic hepatitis and liver cancer, including cell therapies, tumor associated antigen vaccines and tumor neoantigen vaccines. He has published more than 20 papers in peer-reviewed journals and is the inventor of more than 10 patents or computer software copyrights.

Dr. Xie received an MD. (bachelor's degree in clinical medicine) from Medical College of Wuhan University of science and technology in 2006, a master's degree in medicine from the Department of medicine of Peking University in 2009 and a Ph. D. in medicine from China CDC (Center for Disease Control and prevention) in 2018.

Core team

Xingwang Xie3

Ph.D., MD.

Dr. Xingwang Xie founded CorreGene in 2016 and served as board chairman and CEO since 2019.

Dr. Xie is a member of the Multidisciplinary Tumor Diagnosis (MDD) collaboration group of the Tumor Marker Committee of the Chinese Anti-Cancer Association and a member of the Clinical Application Committee of pharmaceutical biotechnology of the China Medicinal Biotech Association (CMBA).

From 2009 to 2019, Dr. Xie started his career as a scientist at the Peking University People’s Hospital, Peking University Hepatology Institute, and has devoted over 10 years to studying the genomics and immunobiology of cancer and their clinical implications. During this period, Dr. Xie been responsible for several major research programs from the National Natural Science Foundation of China and the Beijing Natural Science Foundation. He was also the core members of several projects from National Science and Technology Major Project.

Dr. Xie have participated in many immunotherapy trails for the treatment of chronic hepatitis and liver cancer, including cell therapies, tumor associated antigen vaccines and tumor neoantigen vaccines. He has published more than 20 papers in peer-reviewed journals and is the inventor of more than 10 patents or computer software copyrights.

Dr. Xie received an MD. (bachelor's degree in clinical medicine) from Medical College of Wuhan University of science and technology in 2006, a master's degree in medicine from the Department of medicine of Peking University in 2009 and a Ph. D. in medicine from China CDC (Center for Disease Control and prevention) in 2018.

Core team

Xingwang Xie4

Ph.D., MD.

Dr. Xingwang Xie founded CorreGene in 2016 and served as board chairman and CEO since 2019.

Dr. Xie is a member of the Multidisciplinary Tumor Diagnosis (MDD) collaboration group of the Tumor Marker Committee of the Chinese Anti-Cancer Association and a member of the Clinical Application Committee of pharmaceutical biotechnology of the China Medicinal Biotech Association (CMBA).

From 2009 to 2019, Dr. Xie started his career as a scientist at the Peking University People’s Hospital, Peking University Hepatology Institute, and has devoted over 10 years to studying the genomics and immunobiology of cancer and their clinical implications. During this period, Dr. Xie been responsible for several major research programs from the National Natural Science Foundation of China and the Beijing Natural Science Foundation. He was also the core members of several projects from National Science and Technology Major Project.

Dr. Xie have participated in many immunotherapy trails for the treatment of chronic hepatitis and liver cancer, including cell therapies, tumor associated antigen vaccines and tumor neoantigen vaccines. He has published more than 20 papers in peer-reviewed journals and is the inventor of more than 10 patents or computer software copyrights.

Dr. Xie received an MD. (bachelor's degree in clinical medicine) from Medical College of Wuhan University of science and technology in 2006, a master's degree in medicine from the Department of medicine of Peking University in 2009 and a Ph. D. in medicine from China CDC (Center for Disease Control and prevention) in 2018.

Core team

Xingwang Xie5

Ph.D., MD.

Dr. Xingwang Xie founded CorreGene in 2016 and served as board chairman and CEO since 2019.

Dr. Xie is a member of the Multidisciplinary Tumor Diagnosis (MDD) collaboration group of the Tumor Marker Committee of the Chinese Anti-Cancer Association and a member of the Clinical Application Committee of pharmaceutical biotechnology of the China Medicinal Biotech Association (CMBA).

From 2009 to 2019, Dr. Xie started his career as a scientist at the Peking University People’s Hospital, Peking University Hepatology Institute, and has devoted over 10 years to studying the genomics and immunobiology of cancer and their clinical implications. During this period, Dr. Xie been responsible for several major research programs from the National Natural Science Foundation of China and the Beijing Natural Science Foundation. He was also the core members of several projects from National Science and Technology Major Project.

Dr. Xie have participated in many immunotherapy trails for the treatment of chronic hepatitis and liver cancer, including cell therapies, tumor associated antigen vaccines and tumor neoantigen vaccines. He has published more than 20 papers in peer-reviewed journals and is the inventor of more than 10 patents or computer software copyrights.

Dr. Xie received an MD. (bachelor's degree in clinical medicine) from Medical College of Wuhan University of science and technology in 2006, a master's degree in medicine from the Department of medicine of Peking University in 2009 and a Ph. D. in medicine from China CDC (Center for Disease Control and prevention) in 2018.

Core team

Xingwang Xie6

Ph.D., MD.

Dr. Xingwang Xie founded CorreGene in 2016 and served as board chairman and CEO since 2019.

Dr. Xie is a member of the Multidisciplinary Tumor Diagnosis (MDD) collaboration group of the Tumor Marker Committee of the Chinese Anti-Cancer Association and a member of the Clinical Application Committee of pharmaceutical biotechnology of the China Medicinal Biotech Association (CMBA).

From 2009 to 2019, Dr. Xie started his career as a scientist at the Peking University People’s Hospital, Peking University Hepatology Institute, and has devoted over 10 years to studying the genomics and immunobiology of cancer and their clinical implications. During this period, Dr. Xie been responsible for several major research programs from the National Natural Science Foundation of China and the Beijing Natural Science Foundation. He was also the core members of several projects from National Science and Technology Major Project.

Dr. Xie have participated in many immunotherapy trails for the treatment of chronic hepatitis and liver cancer, including cell therapies, tumor associated antigen vaccines and tumor neoantigen vaccines. He has published more than 20 papers in peer-reviewed journals and is the inventor of more than 10 patents or computer software copyrights.

Dr. Xie received an MD. (bachelor's degree in clinical medicine) from Medical College of Wuhan University of science and technology in 2006, a master's degree in medicine from the Department of medicine of Peking University in 2009 and a Ph. D. in medicine from China CDC (Center for Disease Control and prevention) in 2018.

Core team

Xingwang Xie7

Ph.D., MD.

Dr. Xingwang Xie founded CorreGene in 2016 and served as board chairman and CEO since 2019.

Dr. Xie is a member of the Multidisciplinary Tumor Diagnosis (MDD) collaboration group of the Tumor Marker Committee of the Chinese Anti-Cancer Association and a member of the Clinical Application Committee of pharmaceutical biotechnology of the China Medicinal Biotech Association (CMBA).

From 2009 to 2019, Dr. Xie started his career as a scientist at the Peking University People’s Hospital, Peking University Hepatology Institute, and has devoted over 10 years to studying the genomics and immunobiology of cancer and their clinical implications. During this period, Dr. Xie been responsible for several major research programs from the National Natural Science Foundation of China and the Beijing Natural Science Foundation. He was also the core members of several projects from National Science and Technology Major Project.

Dr. Xie have participated in many immunotherapy trails for the treatment of chronic hepatitis and liver cancer, including cell therapies, tumor associated antigen vaccines and tumor neoantigen vaccines. He has published more than 20 papers in peer-reviewed journals and is the inventor of more than 10 patents or computer software copyrights.

Dr. Xie received an MD. (bachelor's degree in clinical medicine) from Medical College of Wuhan University of science and technology in 2006, a master's degree in medicine from the Department of medicine of Peking University in 2009 and a Ph. D. in medicine from China CDC (Center for Disease Control and prevention) in 2018.

Company history

2016
 
2017
 
2018
 
2019
 
2020
 
2021
 
2022
 
2023
 
2016.04

KRAS G12V specific TCR-T CRTKVA11-01 project was launched

2021.07

Rewarded as a council member of Gene and Cell Technology Research and Application Professional Committee of National Association of Health Industry and Enterprise Management

2021.08

Winner's Prize of "Maker Beijing 2021 innovation and entrepreneurship competition"

2021.09

Obtained ethical approvals for two IIT clinical trials
Top 10 of "2021 Zhongguancun International Frontier Technology Innovation Competition (biomedicine)"

2021.10

Won the honorary certificate of "2021 top 50 most innovative Chinese Biomedical enterprises"

2021.11

Complete the Pre-A round of financing of nearly 100 million yuan

2021.12

Rewarded as the National high-tech enterprise recognition
Launched new R&D center in Bohui Innovation building with upgraded infrastructure, and GMP manufacturing facility in Origin building.

2017.04

KRAS G12V specific TCR-T CRTKVA11-01 project was launched

2021.07

Rewarded as a council member of Gene and Cell Technology Research and Application Professional Committee of National Association of Health Industry and Enterprise Management

2021.08

Winner's Prize of "Maker Beijing 2021 innovation and entrepreneurship competition"

2021.09

Obtained ethical approvals for two IIT clinical trials
Top 10 of "2021 Zhongguancun International Frontier Technology Innovation Competition (biomedicine)"

2021.10

Won the honorary certificate of "2021 top 50 most innovative Chinese Biomedical enterprises"

2021.11

Complete the Pre-A round of financing of nearly 100 million yuan

2021.12

Rewarded as the National high-tech enterprise recognition
Launched new R&D center in Bohui Innovation building with upgraded infrastructure, and GMP manufacturing facility in Origin building.

2018.04

KRAS G12V specific TCR-T CRTKVA11-01 project was launched

2021.07

Rewarded as a council member of Gene and Cell Technology Research and Application Professional Committee of National Association of Health Industry and Enterprise Management

2021.08

Winner's Prize of "Maker Beijing 2021 innovation and entrepreneurship competition"

2021.09

Obtained ethical approvals for two IIT clinical trials
Top 10 of "2021 Zhongguancun International Frontier Technology Innovation Competition (biomedicine)"

2021.10

Won the honorary certificate of "2021 top 50 most innovative Chinese Biomedical enterprises"

2021.11

Complete the Pre-A round of financing of nearly 100 million yuan

2021.12

Rewarded as the National high-tech enterprise recognition
Launched new R&D center in Bohui Innovation building with upgraded infrastructure, and GMP manufacturing facility in Origin building.

2019.04

KRAS G12V specific TCR-T CRTKVA11-01 project was launched

2021.07

Rewarded as a council member of Gene and Cell Technology Research and Application Professional Committee of National Association of Health Industry and Enterprise Management

2021.08

Winner's Prize of "Maker Beijing 2021 innovation and entrepreneurship competition"

2021.09

Obtained ethical approvals for two IIT clinical trials
Top 10 of "2021 Zhongguancun International Frontier Technology Innovation Competition (biomedicine)"

2021.10

Won the honorary certificate of "2021 top 50 most innovative Chinese Biomedical enterprises"

2021.11

Complete the Pre-A round of financing of nearly 100 million yuan

2021.12

Rewarded as the National high-tech enterprise recognition
Launched new R&D center in Bohui Innovation building with upgraded infrastructure, and GMP manufacturing facility in Origin building.

2020.04

KRAS G12V specific TCR-T CRTKVA11-01 project was launched

2021.07

Rewarded as a council member of Gene and Cell Technology Research and Application Professional Committee of National Association of Health Industry and Enterprise Management

2021.08

Winner's Prize of "Maker Beijing 2021 innovation and entrepreneurship competition"

2021.09

Obtained ethical approvals for two IIT clinical trials
Top 10 of "2021 Zhongguancun International Frontier Technology Innovation Competition (biomedicine)"

2021.10

Won the honorary certificate of "2021 top 50 most innovative Chinese Biomedical enterprises"

2021.11

Complete the Pre-A round of financing of nearly 100 million yuan

2021.12

Rewarded as the National high-tech enterprise recognition
Launched new R&D center in Bohui Innovation building with upgraded infrastructure, and GMP manufacturing facility in Origin building.

2021.04

KRAS G12V specific TCR-T CRTKVA11-01 project was launched

2021.07

Rewarded as a council member of Gene and Cell Technology Research and Application Professional Committee of National Association of Health Industry and Enterprise Management

2021.08

Winner's Prize of "Maker Beijing 2021 innovation and entrepreneurship competition"

2021.09

Obtained ethical approvals for two IIT clinical trials
Top 10 of "2021 Zhongguancun International Frontier Technology Innovation Competition (biomedicine)"

2021.10

Won the honorary certificate of "2021 top 50 most innovative Chinese Biomedical enterprises"

2021.11

Complete the Pre-A round of financing of nearly 100 million yuan

2021.12

Rewarded as the National high-tech enterprise recognition
Launched new R&D center in Bohui Innovation building with upgraded infrastructure, and GMP manufacturing facility in Origin building.

2022.04

KRAS G12V specific TCR-T CRTKVA11-01 project was launched

2021.07

Rewarded as a council member of Gene and Cell Technology Research and Application Professional Committee of National Association of Health Industry and Enterprise Management

2021.08

Winner's Prize of "Maker Beijing 2021 innovation and entrepreneurship competition"

2021.09

Obtained ethical approvals for two IIT clinical trials
Top 10 of "2021 Zhongguancun International Frontier Technology Innovation Competition (biomedicine)"

2021.10

Won the honorary certificate of "2021 top 50 most innovative Chinese Biomedical enterprises"

2021.11

Complete the Pre-A round of financing of nearly 100 million yuan

2021.12

Rewarded as the National high-tech enterprise recognition
Launched new R&D center in Bohui Innovation building with upgraded infrastructure, and GMP manufacturing facility in Origin building.

2023.04

KRAS G12V specific TCR-T CRTKVA11-01 project was launched

2021.07

Rewarded as a council member of Gene and Cell Technology Research and Application Professional Committee of National Association of Health Industry and Enterprise Management

2021.08

Winner's Prize of "Maker Beijing 2021 innovation and entrepreneurship competition"

2021.09

Obtained ethical approvals for two IIT clinical trials
Top 10 of "2021 Zhongguancun International Frontier Technology Innovation Competition (biomedicine)"

2021.10

Won the honorary certificate of "2021 top 50 most innovative Chinese Biomedical enterprises"

2021.11

Complete the Pre-A round of financing of nearly 100 million yuan

2021.12

Rewarded as the National high-tech enterprise recognition
Launched new R&D center in Bohui Innovation building with upgraded infrastructure, and GMP manufacturing facility in Origin building.

Qualification & honor

First Prize of the First Digital Intelligence New Industry Healthcare Innovation and Entrepreneurship Competition at the 2022 New Industry 50 Person Forum and Life Health Investment and Financing Summit

High tech enterprises

Zhongguancun High tech Enterprise

Maker Beijing 2021 innovation and entrepreneurship competition

Top 10 of "2021 Zhongguancun International Frontier Technology Innovation Competition (biomedicine)"

National high-tech enterprise recognition

Zhongguancun High tech enterprise

Top50 of "2017 Maker China Innovation and Entrepreneurship Competition"

0First Prize of the First Digital Intelligence New Industry Healthcare Innovation and Entrepreneurship Competition at the 2022 New Industry 50 Person Forum and Life Health Investment and Financing Summit

High tech enterprises

Zhongguancun High tech Enterprise

Maker Beijing 2021 innovation and entrepreneurship competition

Top 10 of "2021 Zhongguancun International Frontier Technology Innovation Competition (biomedicine)"

National high-tech enterprise recognition

Zhongguancun High tech enterprise

Top50 of "2017 Maker China Innovation and Entrepreneurship Competition"